Our Activities

Integrative Research on Structure and Function of various Leucine-Rich Repeat (LRR)-containing Proteins


  • Identifying novel binding targets for LRR-containing proteins

  • Determining 3D structure of LRR-containing proteins in complex with novel binding targets and their supramolecular signaling complexes using Cryo-EM and X-ray crystallography

  • Investigating the molecular and cellular mechanism of LRR-containing proteins

  • Uncovering the physiological and pathological roles of LRR-containing proteins

2022 International Conference : Asian Crystallographic Association(AsCA) was held on 30 October ~ 3 November 2022.

Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex. (Nature Communications, 2022)